FULL TURNKEY SOLUTIONS and THE LATEST NVIDIA GPUs
new tools for automated high resolution
cryo-EM structure determination
Relion is an image processing software designed specifically for cryo-electron microscopy (cryo-EM). Developed by the group of Sjors Scheres at the MRC Laboratory of Molecular Biology, the Relion framework is revolutionizing the cryo-EM field. It is a stand alone computer program built for the refinement of macromolecular structures by single-particle analysis of electron cryo-microscopy data. Relion employs an empiracal Bayesian approach for refinement of multiple 3D reconstructions or 2D class averages. With alternative approaches often relying on user expertise for the tuning of parameters, Relion can find an optimal way of filtering the data automatically.
The new functionality in Relion-3 allows faster, more automated and higher resolution cryo-EM structure determination compared to previous versions. GPU acceleration makes it possible to use a much wider range of hardware efficiently for Relion.
Corrections for per-particle defocus variations, beam tilt and the Ewald sphere already improve resolutions for currently available data sets, and will become even more important as the resolutions of typical cryo-EM structures improve in the future.
All NVidia GeForce systems are fully validated for numerical correctness using custom validation suites.