Scipion

last VERSION: SCIPION 3.0

SCIPION is an image processing framework to obtain 3D models of macromolecular complexes using Cryo-electron Microscopy. It is very well integrated with High-Performance Computing environments and combine existing software allowing strucutral biologists to switch from one package to another. So it allows the execution of reusable, standardized, traceable and reproducible image-processing protocols that incorporate tools from different programs.

Although Scipion developers started with single particle analysis methods, this software is currently expanding its toolset to include atomic modelling and tomography. In november 2020 was released Scipion 3.0, which have several new features, improvements and fixed bugs compared with the old version. Professionals from all around the world have contributed to develop this project and are using it already in Cryo-EM investigations.

SCIPION HIGHLIGHTS

Scipion 3.0 will process your acquired images on the fly and will provide feedback to help you make decisions while the microscope is collecting data. The highlights of the last version of Scipion are numerous.

Organisation: Scipion will help you to organise your projects. Differently to Relion, Scipion can be launched anywhere. So you will be able to select the project you want to work on.
Integration: Designed to integrate and be integrated. Most popular image processing packages, like Relion 3, motioncor2, ctffind4, crYOLO, Xmipp and tomography packages, are integrated.
Analysis: When analyzing the resulting class reconstructions, the slices view will offer a much better impression of unresolved heterogeneity.
Automation: You can automate your acquisition (drift, gain, CTF, resolution, defocus) as well as your system (GPU's, memory).
Workflows templates: You can define as many workflows as you wish. You can save them as templates too.

Image: 3D reconstruction of chikungunya virus.

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